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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SPR
All Species:
24.24
Human Site:
S145
Identified Species:
41.03
UniProt:
P35270
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35270
NP_003115.1
261
28048
S145
V
L
K
A
F
P
D
S
P
G
L
N
R
T
V
Chimpanzee
Pan troglodytes
XP_525784
261
27897
S145
V
L
K
A
F
P
A
S
P
G
L
N
R
T
V
Rhesus Macaque
Macaca mulatta
XP_001103332
261
28016
S145
V
L
K
A
F
P
A
S
P
G
L
N
R
T
V
Dog
Lupus familis
XP_540234
267
28592
S151
I
L
K
A
F
P
D
S
P
G
L
S
R
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q64105
261
27865
S146
T
L
N
A
F
Q
D
S
P
G
L
S
K
T
V
Rat
Rattus norvegicus
P18297
262
28110
S146
T
L
N
A
F
S
N
S
P
G
L
S
K
T
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520473
236
25629
S106
I
L
R
A
F
P
P
S
P
G
L
T
R
T
V
Chicken
Gallus gallus
Q8JIS3
246
26149
A126
I
V
A
R
Q
M
I
A
Q
G
L
P
G
A
I
Frog
Xenopus laevis
Q7ZY31
263
28687
R148
L
L
K
T
F
P
R
R
P
D
L
Q
R
L
V
Zebra Danio
Brachydanio rerio
NP_001019601
261
28523
R145
V
L
R
T
Y
P
K
R
S
G
L
T
R
V
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624245
354
39811
N237
I
M
K
I
F
N
K
N
T
N
T
K
K
L
V
Nematode Worm
Caenorhab. elegans
Q21929
251
27201
D131
L
V
A
R
N
F
V
D
R
Q
I
K
G
S
I
Sea Urchin
Strong. purpuratus
XP_783056
275
30198
R150
F
L
R
T
F
P
H
R
E
G
L
R
R
T
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40579
254
27462
L125
V
G
I
A
L
P
E
L
K
K
T
N
G
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
96.9
80.9
N.A.
74.3
74.4
N.A.
46.3
26.4
55.5
52.4
N.A.
N.A.
25.4
26
39.6
Protein Similarity:
100
98
99.6
89.1
N.A.
86.5
88.1
N.A.
58.6
44.8
69.9
74.3
N.A.
N.A.
41.5
46.3
58.5
P-Site Identity:
100
93.3
93.3
86.6
N.A.
66.6
60
N.A.
73.3
13.3
53.3
40
N.A.
N.A.
20
0
46.6
P-Site Similarity:
100
93.3
93.3
100
N.A.
80
80
N.A.
86.6
40
60
60
N.A.
N.A.
46.6
33.3
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
58
0
0
15
8
0
0
0
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
22
8
0
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
72
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
0
72
0
0
22
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
29
0
8
8
0
0
8
0
0
0
8
0
0
0
29
% I
% Lys:
0
0
43
0
0
0
15
0
8
8
0
15
22
0
0
% K
% Leu:
15
72
0
0
8
0
0
8
0
0
79
0
0
15
0
% L
% Met:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
8
8
8
8
0
8
0
29
0
8
0
% N
% Pro:
0
0
0
0
0
65
8
0
58
0
0
8
0
0
0
% P
% Gln:
0
0
0
0
8
8
0
0
8
8
0
8
0
0
0
% Q
% Arg:
0
0
22
15
0
0
8
22
8
0
0
8
58
0
0
% R
% Ser:
0
0
0
0
0
8
0
50
8
0
0
22
0
8
0
% S
% Thr:
15
0
0
22
0
0
0
0
8
0
15
15
0
58
0
% T
% Val:
36
15
0
0
0
0
8
0
0
0
0
0
0
8
72
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _